Clinical Manifestation of Type I Diabetes Mellitus Patients Presented in a Tertiary Care Hospital in Karachi

Authors

  • Saadullah Chachar
  • Muhammad Ashfaq
  • Bader-U- Nisa
  • Nadeem Ahmed
  • Aijaz Ahmed
  • Mohsina Noor Ibrahim

Abstract

OBJECTIVE: To determine the frequency of clinical manifestation of type 1 diabetes mellitus patients presented in tertiary care hospitals in Karachi
METHODOLOGY: A descriptive cross-sectional study was conducted from July 2015 to January 2016 at Out Patient Department of National Institute of Child Health, Karachi, Pakistan. A total of 90 children aged less than 18 years of either gender with type 1 diabetes mellitus (T1DM) were included through the non-probability consecutively sampling technique. Children who were immunocompromised or taking any drug which could cause hyperglycemia were excluded from the study. Various clinical presentations in terms of Diabetic ketoacidosis (DKA), weight loss, polydipsia, and polyuria were recorded. Data were
entered and analyzed by using SPSS version 19.0.
RESULTS: The age range was from 1 to 18 years (average age of 8.5+4.15 years) with a mean duration of symptoms 2.3+1.2 weeks. Out of 90 patients, 48 (53%) were male and 42 (47%) were female. There were 56(62.2%) were with DKA, 33(36.66%) were with weight loss, 65 (72.2%) were with polydipsia, and 76 (84.4%) were with polyuria. A significant association of polyuria was observed with the age of the patients (p-value <0.001) whereas the duration of symptoms was found to be significantly associated
with DKA (p-value <0.001) and polyuria (p-value 0.032).
CONCLUSION: The frequency of clinical presentations at the onset of type I diabetes mellitus (T1DM) is significant. Polydipsia, polyuria, and diabetic ketoacidosis are the most common symptoms of presentation.
KEYWORDS: Clinical manifestations, type 1 diabetes mellitus, diabetic ketoacidosis, polyuria, polydipsia, tertiary care.

Downloads

Published

03-01-2022

How to Cite

1.
Chachar S, Ashfaq M, Nisa B-U-, Ahmed N, Ahmed A, Ibrahim MN. Clinical Manifestation of Type I Diabetes Mellitus Patients Presented in a Tertiary Care Hospital in Karachi. J Liaq Uni Med Health Sci [Internet]. 2022 Jan. 3 [cited 2024 Nov. 13];20(5):319-23. Available from: http://ojs.lumhs.edu.pk/index.php/jlumhs/article/view/815

Issue

Vol. 20 No. 5 (2021): Journal of Liaquat University of Medical & Health Sciences

Section

Original Articles

License

Copyright (c) 2022 Journal of Liaquat University of Medical & Health Sciences

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

Submission of a manuscript to the journal implies that all authors have read and agreed to the content of the undertaking form or the Terms and Conditions.

When an article is accepted for publication, the author(s) retain the copyright and are required to grant the publisher the right of first publication and other non-exclusive publishing rights to JLUMHS.

Articles published in the Journal of Liaquat University of Medical & health sciences are open access articles under a Creative Commons Attribution-Noncommercial - Share Alike 4.0 License. This license permits use, distribution and reproduction in any medium; provided the original work is properly cited and initial publication in this journal. This is in accordance with the BOAI definition of open access. In addition to that users are allowed to remix, tweak and build upon the work non-commercially as long as appropriate credit is given and the new creations are licensed under the identical terms. Or, in certain cases it can be stated that all articles and content there in are published under creative commons license unless stated otherwise.