Maternal Transmission of Human Immunodeficiency Virus to Infants in A Tertiary Care Hospital in Pakistan
Abstract
Objective: To determine frequency of transmission of HIV from mother to child at Aziz Bhatti Shaheed Teaching Hospital Gujrat.
Methodology: Cross-sectional study conducted at Aziz Bhatti Shaheed Teaching Hospital Gujrat in Department of Gynecology and Obstetric Unit II from January 2012 to March 2019 using non-probability consecutive sampling. Patients who tested positive for HIV and reached full term were included. Mothers were started ART at time of diagnosis. Infant prophylaxis was done according to WHO guidelines. Counseling regarding breastfeeding was done. HIV status of infants was noted at 12 weeks after birth. A total of 51 patients were included. SPSS 20.0 was used for data analysis.
Results: Fifty-one patients included having mean age 29.45+3.15 years. All patients were diagnosed during pregnancy. ART was initiated in 17(33.3%) in first trimester, 10(19.6%) in second trimester, 20(39.2%) in third trimester and in 4(7.8%) post-partum. At 6 weeks follow up of mothers, 46(90.2%) were stable, 3(5.9%) lost to follow up and 2(3.9%) mothers died post-partum at home. At 12 weeks follow up of infants 39(76.5%) tested negative for HIV, 2(3.9%) were tested positive, 7(13.7%) lost to follow up and 3(5.9%) infants died during this period. In alive and tested infants 2 out of 41 were tested positive, making HIV transmission to children from mothers to be 4.9%.
Conclusion: HIV transmission to children form mothers is high in our population and there is need for active screening of all pregnant mothers.
Key Words: Mother to Child HIV Transmission, HIV, HIV in Infants, Pregnancy, AIDS
Downloads
Published
How to Cite
Issue
Section
License
Submission of a manuscript to the journal implies that all authors have read and agreed to the content of the undertaking form or the Terms and Conditions.
When an article is accepted for publication, the author(s) retain the copyright and are required to grant the publisher the right of first publication and other non-exclusive publishing rights to JLUMHS.
Articles published in the Journal of Liaquat University of Medical & health sciences are open access articles under a Creative Commons Attribution-Noncommercial - Share Alike 4.0 License. This license permits use, distribution and reproduction in any medium; provided the original work is properly cited and initial publication in this journal. This is in accordance with the BOAI definition of open access. In addition to that users are allowed to remix, tweak and build upon the work non-commercially as long as appropriate credit is given and the new creations are licensed under the identical terms. Or, in certain cases it can be stated that all articles and content there in are published under creative commons license unless stated otherwise.