Evaluation of Pattern and Impact of Electrolytes Abnormalities in Critically Ill Covid-19 Patients


  • Anita Haroon
  • Syed Ali Abbas
  • Amanullah Khan
  • Momina Ali
  • Rija Qazi
  • Ajeet Kumar


Objective: To evaluate the pattern of serum electrolytes abnormalities and their impact on ICU admitted Covid-19 patient outcomes.

Methodology: This retrospective study was carried out at OMI hospital and Dr. Ziauddin Hospital, Karachi, Pakistan, between August to December 2020. Total 102 PCR positive, ICU admitted with severe Covid-19 patients as per WHO criteria were included. The patient's demographic characteristics, clinical features including co-morbidities, electrolytes reports at the time of admission, length of ICU and/or hospital stay, and outcome (expired/survived) were evaluated.

Results: Biochemical testing found abnormal electrolyte levels in 90.2% ICU admitted Covid-19 patients. Electrolytes abnormalities including hyponatremia 45.1%, hypermagnesemia 40.2%, hypocalcemia 31.4%, hyperchloremia23.5% and hyperphosphatemia in 20.6% patients. Out of the total, 28.4% of patients needed invasive respiratory support, and 37.3% could not survive. A higher incidence of mortality (39.1% vs. 20%) was seen in patients with electrolytes abnormalities compared to those presented with normal values.

Conclusion: Electrolyte abnormalities were found in 90% of the ICU Admitted Covid-19 patients. The most common abnormalities found among the patients were hyponatremia, hypermagnesemia, and Hypocalcemia. The findings revealed that several electrolyte imbalances harm patients' in-hospital outcomes. Electrolyte assessment of Covid-19 patients at the time of admission would be helpful in risk stratification for adverse outcomes.

Keywords: Covid-19, critically Ill, ICU stay, serum electrolytes, abnormalities, respiratory support, death.




How to Cite

Haroon A, Abbas SA, Khan A, Ali M, Qazi R, Kumar A. Evaluation of Pattern and Impact of Electrolytes Abnormalities in Critically Ill Covid-19 Patients . J Liaq Uni Med Health Sci [Internet]. 2022 Apr. 11 [cited 2024 Jun. 20];21(01):16-22. Available from: http://ojs.lumhs.edu.pk/index.php/jlumhs/article/view/679