Medicinal Properties of Illicium Verum Hook. F.

Authors

  • Asra Khan Pahore
  • Shagufta Khan
  • Nasim Karim

Abstract

Medicinal plants have active elements that can be used for cures or making drug precursors. According to the World Health Organization, 80% of the world's population depends on these plants as traditional treatments to meet their health care needs. Illicium verum Hook. F. (star anise) is an extensively used spice in traditional Chinese cuisine as a flavoring agent or a historical medicine for vomiting, stomachache, flatulence, and rheumatism and is included in the Chinese Pharmacopoeia. Some active components of star anise are essential oil, anethole, trans-anethole,  sesquiterpenoids, shikimic acid, lignans, etc., which possess anxiolytic, neuro-protective, antibacterial, antifungal, anti-inflammatory, antiemetic, anti-flu, antidiarrheal, antispasmodic, anti-diabetic, antioxidant, anti-thrombotic, and antitumour effects that are discussed in this review article.

References

Elmasry TA, Al-Shaalan NH, Tousson E, El-Morshedy K, Al-Ghadeer A. Star anise extracts modulation of reproductive parameters, fertility potential and DNA fragmentation induced by growth promoter Equigan in rat testes. Braz J Pharm Sci. 2018; 54(1): 17261-70. doi: 10.1590/s2175-97902018000117261.

Destro BG, Jorge RM, Mathias AL. Optimization of high-concentration trans-anethole production through hydro distillation of star anise. Braz J Chem Eng. 2019; 36(2): 823-30. doi: 10.1590/0104-6632.20190362s20180203.

Boota T, Rehman R, Mushtaq A, Kazerooni EG. Star anise: A review on benefits, biological activities and potential uses. Int J Chem Biochem. 2018; 14: 110-4.

Peng W, Lin Z, Wang L, Chang J, Gu F, Zhu X. Molecular characteristics of Illicium verum extractives to activate acquired immune response. Saudi J Biol Sci. 2016; 23(3): 348-52. doi: 10.1016/j.sjbs.2015.10.027.

Nguyen TT, Trinh NY, Le PT. Recovery Yield and Bioactivities Evaluation on Essential Oil and Ethanolic Extract of Star Anise (Illicium verum Hook. f.). Chem Eng Trans. 2021; 83: 205-10. doi: 10.3303/CET2183035.

Li SN, Sun JF, Wang JM, Jin L, Zong TQ, Zhou W et al. Two new phenolic glycosides from the fruits of Illicium verum. J Asian Nat Prod Res. 2022; 24(1): 31-8. doi: 10.1080/10286020.2021.1871606.

Shi Y, Chen G, Chen K, Chen X, Hong Q, Kan J. Assessment of fresh star anise (Illicium verum Hook. f.) drying methods for influencing drying characteristics, color, flavor, volatile oil and shikimic acid. Food Chem. 2021; 342: 128359-70.

doi: 10.1016/j.foodchem.2020.128359.

Sharafan M, Jafernik K, Ekiert H, Kubica P, Kocjan R, Blicharska E et al. Illicium verum (Star Anise) and Trans-Anethole as Valuable Raw Materials for Medicinal and Cosmetic Applications. Molecules. 2022; 27(3): 650-65. doi: 10.3390/molecules27030650.

de Oliveira Silva MR, Santos MH. Medical plants: from Colonial Brazil to their indication by the National Single Health System–SHS. Int J Adv Eng Res Sci. 2019; 6(9): 165-173. doi: 10.22161/ijaers.69.19.

Boy HI, Rutilla AJ, Santos KA, Ty AM, Alicia IY, Mahboob T et al. Recommended medicinal plants as source of natural products: a review. Digital Chin Med. 2018; 1(2): 131-42. doi: 10.1016/S2589-3777(19)30018-7.

Veiga M, Costa EM, Silva S, Pintado M. Impact of plant extracts upon human health: A review. Crit Rev Food Sci Nutr. 2020; 60(5): 873-86. doi: 10.1080/10408398.2018.1540969.

Nankaya J, Gichuki N, Lukhoba C, Balslev H. Medicinal plants of the Maasai of Kenya: a review. Plants. 2019; 9(1): 44-60. doi: 10.3390/plants9010044.

Jamshidi-Kia F, Lorigooini Z, Amini-Khoei H. Medicinal plants: Past history and future perspective. J HerbMed Pharmacol. 2017; 7(1): 1-7. doi: 10.15171/jhp.2018.01.

Assiry AA, Karobari MI, Bhavikatti SK, Marya A. Crossover analysis of the astringent, antimicrobial, and anti-inflammatory effects of Illicium verum/star anise in the oral cavity. Biomed Res Int. 2021; 2021: 1-6. doi: 10.1155/2021/5510174.

Sachan AK, Kumar S, Kumari K, Singh D. Medicinal uses of spices used in our traditional culture: Worldwide. J Med Plants Stud. 2018; 6(3): 116-22.

Vecchio MG, Gulati A, Minto C, Lorenzoni G. Pimpinella Anisum and Illicium Verum: The Multifaceted Role of Anise Plants. Open Agric. 2016; 10(1): 81-6. doi: 10.2174/1874331501610010084.

Shahrajabian MH, Sun W, Cheng Q. Survey on Chemical Constituent, Traditional and Modern Pharmaceutical and Health Benefits of Chinese Star Anise, a Treasure from the East. Phcog Commn. 2021; 11(1): 31-5. doi: 10.5530/pc.2021.1.7.

Patra JK, Das G, Bose S, Banerjee S, Vishnuprasad CN, del Pilar Rodriguez?Torres M et al. Star anise (Illicium verum): Chemical compounds, antiviral properties, and clinical relevance. Phytother Res. 2020; 34(6): 1248-67. doi: 10.1002/ptr.6614.

Nguyen TT, Trinh NY, Le PT. Recovery Yield and Bioactivities Evaluation on Essential Oil and Ethanolic Extract of Star Anise (Illicium verum Hook. f.). Chem Eng Trans. 2021; 83: 205-10. doi: 10.3303/CET2183035.

Shahrajabian MH, Sun W, Cheng Q. Chinese star anise (Illicium verum) and pyrethrum ('Chrysanthemum cinerariifolium') as natural alternatives for organic farming and health care-a review. Aust J Crop Sci. 2020; 14(3): 517-23. doi: 10.21475/ajcs.20.14.03.p2209.

Zhang G, Yuan C, Sun Y. Effect of selective encapsulation of hydroxypropyl-?-cyclodextrin on components and antibacterial properties of star anise essential oil. Molecules. 2018; 23(5): 1126-40. doi: 10.3390/molecules23051126.

Sayyar HT. Exotic Spice Illicium Verum Hook. F. J Bahria Univ Med Dent Coll. 2018; 8(3): 189-93. doi: 10.51985/JBUMDC2018044.

Yu C, Zhang J, Wang T. Star anise essential oil: Chemical compounds, antifungal and antioxidant activities: a review. J Essent Oil Res. 2021; 33(1): 1-22. doi: 10.1080/10412905.2020.1813213.

Alhajj MS, Qasem MA, Nabi AR, Al-Mufarrej SI. In-vitro antibacterial and antifungal effects of high levels of Chinese star anise. Braz J Poultry Sci. 2019; 21(1): 001-008. doi: 10.1590/1806-9061-2016-0427.

Asif M, Yehya AH, Al-Mansoub MA, Revadigar V, Ezzat MO, Ahamed MB et al. Anticancer attributes of Illicium verum essential oils against colon cancer. S Afr J Bot. 2016; 103: 156-61. doi: 10.1016/j.sajb.2015.08.017.

Bhatti HA, Khan S, Faizi S, Abbas G, Ali I, Jawaid S et al. Protocatecheuic acid underlies the antioxidant activity exhibited by Illicium verum fruit. J Anal Pharm Res. 2017; 6(3): 00177-81. doi: 10.15406/japlr.2017.06.00177.

Anise PE. Antioxidant and Anti-Diabetic activities of Polyphenol-enriched Star Anise (Illicium verum) seeds extract. Int J Biotechnol Biochem. 2018; 14(2): 77-84.

Yang EC, Hsieh YY, Li-Yeh C. Comparison of the Phytochemical Composition and Antibacterial Activities of the Various Extracts from Leaves and Twigs of Illicium verum. Molecules. 2021; 26(13): 3909-24. doi: 10.3390/molecules26133909.

Salem MA, El-Shiekh RA, Hashem RA, Hassan M. In vivo Antibacterial Activity of Star Anise (Illicium verum Hook.) Extract Using Murine MRSA Skin Infection Model in Relation to Its Metabolite Profile. Infect Drug Resist. 2021; 14: 33-48. doi: 10.2147/IDR.S285940.

Luís Â, Sousa S, Wackerlig J, Dobusch D, Duarte AP, Pereira L et al. Star anise (Illicium verum Hook. f.) essential oil: Antioxidant properties and antibacterial activity against Acinetobacter baumannii. Flavour Fragr J. 2019; 34(4): 260-70. doi: 10.1002/ffj.3498.

Paul R, Geetha RV. Evaluation of anti-inflammatory action of Illicium verum-An in vitro study. Drug Discov Today. 2018; 10(12): 2441-2444.

Sung YY, Kim YS, Kim HK. Illicium verum extract inhibits TNF-?-and IFN-?-induced expression of chemokines and cytokines in human keratinocytes. J Ethnopharmacol. 2012; 144(1): 182-9. doi: 10.1016/j.jep.2012.08.049.

Maimoona A. Phytochemical analysis and antiemetic activity of Illicium verum Hook. f. fruit by chick emesis model. J Pharmacogn Phytochem. 2016; 5(6): 185-8.

Kshirsagar PR, Pai SR, Vyavahare GD, Bapat VA, Desai NS. Prospecting alternative source of shikimic acid from clusiaceae of Western Ghats, India and evaluating discrepancies with reference to seasonal variation, developmental stage and sex of Mammea suriga. Ind Crops Prod. 2020; 149: 112354-61. doi: 10.1016/j.indcrop.2020.112354.

Díaz-Quiroz DC, Cardona-Félix CS, Viveros-Ceballos JL, Reyes-González MA, Bolívar F, Ordoñez M et al. Synthesis, biological activity and molecular modelling studies of shikimic acid derivatives as inhibitors of the shikimate dehydrogenase enzyme of Escherichia coli. J Enzyme Inhib Med Chem. 2018; 33(1): 397-404. doi: 10.1080/14756366. 2017.1422125.

Palai S, Dehuri M, Patra R. Spices boosting immunity in COVID-19. Ann Phytomed. 2020; 9(2): 80-96.

Sayyar HT, Raza ML, Baqir SR. Evaluation of Antiamnesic and Cholinesterase inhibitory effects of Illicium verum hook. f (Star anise) against Scopolamine induced memory impairment in Mice. J Bahria Univ Med Dent Coll. 2023; 13(01): 08-12.

Chouksey D, Upmanyu N, Pawar RS. Central nervous system activity of Illicium verum fruit extracts. Asian Pac J Trop Dis. 2013; 6(11): 869-75. doi: 10.1016/j.fitote.2010.11.003.

McCallum RW, González-Stuart AE. Medicinal Plants Used for Digestive Disorders – What the Gastroenterologist Needs to Know. Pract Gastroenterol. 2015; 13: 12-25.

Díaz A, Vargas-Perez I, Aguilar-Cruz L, Calva-Rodríguez R, Treviño S, Venegas B et al. A mixture of chamomile and star anise has anti-motility and antidiarrheal activities in mice. Rev Bras Farmacogn. 2014; 24: 419-24. doi: 10.1016/j.bjp.2014.07.016.

Shaikh TA. Effect Effects of Methanol Extract of Illicium verum hook. f on Coagulation Parameters: Effects of Methanol Extract of Illicium verum hook. f. Pak J Med Dent. 2020; 9(1): 22-8. doi: 10.36283/PJMD9-1/006.

Pandit K, Kaur S, Kumar A, Bhardwaj R, Kaur S. Trans-Anethole abrogates cell proliferation and induces apoptosis through the mitochondrial-mediated pathway in human osteosarcoma cells. Nutr Cancer. 2021; 73(9): 1727-45. doi: 10.1080/01635581.2020.1803927.

Downloads

Published

2024-04-01

How to Cite

1.
Pahore AK, Khan S, Karim N. Medicinal Properties of Illicium Verum Hook. F. J Liaq Uni Med Health Sci [Internet]. 2024 Apr. 1 [cited 2024 Apr. 22];23(01):11-4. Available from: http://ojs.lumhs.edu.pk/index.php/jlumhs/article/view/899