Prevalence and Risk Factors of Metabolic Syndrome in Women with Polycystic Ovarian Syndrome

Authors

  • Zahra Wasim
  • Tahira Riaz
  • Sadaf Shafique
  • Ghana Shahid
  • Islam Bano
  • Huma Shehzadi

Keywords:

Hypertension, metabolic syndrome, obesity, polycystic ovarian syndrome, triglyceride

Abstract

Objective: To find out the prevalence and risk factors of metabolic syndrome among females presenting with polycystic ovarian syndrome (PCOS) in a tertiary care setting.

Methodology: This cross-sectional study was performed at the Department of Obstetrics and Gynecology, The Combined Military Hospital (CMH), Rawalpindi, Pakistan, from January to December 2022. A total of 277 non-pregnant females aged 18-35 years and diagnosed with PCOS presenting in the outpatient department were analyzed. Metabolic syndrome was diagnosed according to the AHA/NHLBI (ATP III) definition, while PCOS was labeled as per Rotterdam consensus guidelines. Prevalence of metabolic syndrome and associated risk factors were noted.

Results: In a total of 277 women with PCOS, the mean age was 27.4±5.6 years, while 149 (53.8%) women were aged between 18 and 25. The residential status of 189 (68.2%) women was rural. There were 81 (29.2%) women with PCOS who were found to have metabolic syndrome. Waist circumference ? 80 cm (p=0.0031), HDL cholesterol < 50 mg/dl (p<0.0001), triglyceride ? 150 mg/dl (p<0.0001), hypertension (p<0.0001) and fasting blood glucose (FBG) > 110 mg/dl (p<0.0001) were having significant association with the presence of metabolic syndrome.

Conclusion: A high prevalence of metabolic syndrome was found among women with polycystic ovarian syndrome. Central obesity, hypertension and abnormal levels of FBG, triglyceride and high-density lipoprotein were found to have a significant association with MBS among women with PCOS.

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Published

28-06-2024

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1.
Zahra Wasim, Tahira Riaz, Sadaf Shafique, Ghana Shahid, Islam Bano, Huma Shehzadi. Prevalence and Risk Factors of Metabolic Syndrome in Women with Polycystic Ovarian Syndrome. J Liaq Uni Med Health Sci [Internet]. 2024 Jun. 28 [cited 2024 Nov. 22];23(02):121-4. Available from: http://ojs.lumhs.edu.pk/index.php/jlumhs/article/view/1209

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Vol. 23 No. 02 (2024): Journal of Liaquat University of Medical & Health Sciences

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Original Articles

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