@article{Khaliq_Ali_2023, title={Diagnostic Utility of Bone Marrow Biopsy/ Bone Marrow Culture in Pyrexia of Unknown Origin: A Ten-Year Retrospective Analysis}, volume={22}, url={http://ojs.lumhs.edu.pk/index.php/jlumhs/article/view/1007}, abstractNote={<p><strong>Objective: </strong>This study was carried out to assess the diagnostic utility of BMB and BMC in patients with PUO.</p> <p><strong>Methodology</strong>: This retrospective cross-sectional study was conducted at Fauji Foundation Hospital, Rawalpindi. The clinical, laboratory and radiological records from January 2012 - December 2021 were retrieved from our hospital management information system for this study. Data from 63 patients with PUO were analyzed according to Petersdorf criteria.</p> <p><strong>Results:</strong> Out of 63 patients with PUO, BMB was diagnostic in 25 (39.68%) patients. The leading cause of PUO was infectious disorders (mycobacterium tuberculosis, visceral leishmaniasis, malaria), followed by inflammatory disorders and hematological malignancies. In 38 (60.31%) patients, BMB could not detect any underlying pathology. BMC showed growth in only 03(4.76%) patients, and the diagnostic yield of BMC was meagre.</p> <p><strong>Conclusion:</strong> BMB is essential in establishing a diagnosis in patients with PUO. Infectious diseases are the leading cause of PUO, and BMC should not be included as a routine investigation in the initial evaluation of a patient with PUO.</p> <p> </p>}, number={01}, journal={Journal of Liaquat University of Medical & Health Sciences}, author={Khaliq, Sehar and Ali, Haider}, year={2023}, month={Mar.}, pages={40–43} }